Sultana was running out of options, and she had to act quickly. She researched the anecdotal reports on treatments with potential against the coronavirus. One was a powerful anti-inflammatory drug often used to treat rheumatoid arthritis, an autoimmune disease in which the immune system also goes into overdrive, attacking the body. She reasoned that Fiske might respond to this drug, called Actemra, which inhibits a particular cytokine called IL-6. Following promising results in China when the drug was used off-label in Covid-19 patients, the FDA had approved its use in U.S. clinical trials in March. (Reports from Italy using a similar drug, Kezvara, showed similar outcomes; it is now in global clinical trials.)Evidence-based garbage.
None of this is how medicine is supposed to be practiced in the data-centric 21st century, but Sultana and her colleagues across the world have found themselves flinging any plausible weapon at the virus.
Tuesday, May 05, 2020
"None of this is how medicine is supposed to be practiced in the data-centric 21st century"
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